Do Over-The-Counter Brain Health Supplements Really Work?
- Team Writer
- Apr 4
- 3 min read

Many people want to keep their brains sharp, especially as they age. In the U.S., over-the-counter (OTC) supplements for brain health have become popular. These products claim to improve memory, focus, and brain function. But do they work? The Dementia Society of America® explains what these supplements are, what’s in them, and whether they help your brain.
What Are Brain Health Supplements?
Brain health supplements are pills, powders, or drinks that people buy without a doctor’s prescription. They are sold in stores and online, often labeled as “memory boosters” or “focus enhancers.” These supplements contain ingredients like:
Omega-3 fatty acids – found in fish oil – may support brain function.
B Vitamins – contribute to energy levels and brain cell health.
Ginkgo Biloba – a plant extract that some believe enhances memory.
Caffeine – present in coffee and tea, it can increase alertness.
Herbs such as ashwagandha – thought to reduce stress.
Do Brain Health Supplements Actually Work?
Scientists are still unsure if these supplements improve brain function. Some studies suggest that certain ingredients, like omega-3s and B vitamins, may support brain health, especially for people who don’t get enough from food. However, many other ingredients have little to no scientific proof that they work.
There Is No Magic Pill – The U.S. Food and Drug Administration (FDA) does not test supplements for effectiveness before they are sold. This means companies can claim their products help the brain, even without strong evidence.
Not a Cure for Memory Loss – Some supplements say they prevent the diseases that cause Dementia or Alzheimer’s disease, but no supplement has been proven to do this. The Dementia Society of America reminds the public that people should be careful of products that make these claims.
Are There Any Risks?
While most brain supplements are safe, some have side effects or may interact with medications.
Too Much of a Good Thing – High doses of specific vitamins, like B6 or B12, can cause nerve problems.
Blood Thinners – Ingredients like Ginkgo Biloba may thin the blood and cause bleeding problems.
Fake or Unregulated Products—Some supplements do not contain what they promise since the U.S. supplement industry is little regulated.
Better Ways to Support Brain Health
Instead of relying on supplements, scientists recommend proven methods to keep your brain healthy:
Eat a Brain-Boosting Diet – Foods like fish, nuts, berries, and leafy greens help brain function.
Exercise Regularly – Physical activity improves blood flow to the brain.
Get Enough Sleep – The brain needs rest to function correctly.
Stay Mentally Active – Reading, puzzles, and learning new things help keep your brain sharp.
Stay Social – Talking to friends and family helps memory and mental well-being.
Conclusion
While brain health supplements are popular in the U.S., there is little evidence that they enhance memory or focus. Some ingredients may have mild benefits, but do not cure memory loss or brain diseases. Instead of relying on supplements, people can keep their brains strong by eating well, exercising, and staying mentally active. A healthy lifestyle is the best way to support brain health for life!
Author: AI-Assisted Human-Edited Staff Writer
We do not endorse nor guarantee products, comments, suggestions, links, or other forms of content contained within blog posts that have been provided to us with permission, paid or otherwise. Dementia Society does not provide medical advice. Please consult your doctor. www.DementiaSociety.org
Additional Reading:
National Institutes of Health (NIH) – Office of Dietary Supplements.
Dietary Supplements for Cognitive Function, Dementia, and Brain Health. https://ods.od.nih.gov/
U.S. Food and Drug Administration (FDA).
Caution on Dietary Supplements for Brain Health and Memory Claims. https://www.fda.gov/
National Center for Complementary and Integrative Health (NCCIH).
Can Supplements Help with Memory and Thinking?
Harvard Medical School.
Brain Supplements: What Works and What Doesn’t?
https://www.health.harvard.edu/
American Academy of Neurology (AAN).
The Truth About Over-the-Counter Memory Supplements.
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