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Young-Onset

Young-Onset is often also referred to as "Early-Onset." Yet, it should be differentiated from another commonly used phrase: "Early Stage Dementia," which is more appropriate to describe someone in the early stages of Dementia, at any age.

 

"Young-Onset Dementia is conventionally thought to include patients with onset before 65 years of age. This cutoff point is indicative of a sociological partition in terms of employment and retirement age, but this age has no specific biological significance and there is a range of disease features across this arbitrary divide."

Source: click here.

 

"Some people with early-onset Alzheimer's [Dementia] have the common form of the disease, and experts don't know why these people get the disease at a younger age than others do. For most, however, early-onset Alzheimer's runs in the family. They're likely to have a parent or grandparent who also developed Alzheimer's at a younger age.

 

Early-onset Alzheimer's that runs in families is linked to three genes that differ from the APOE gene that can increase your risk of Alzheimer's in general. The genetic path of inheritance is much stronger in early-onset Alzheimer's. If you have a genetic mutation in one of those three genes — the APP, PSEN 1, or PSEN 2 — you may develop Alzheimer's before age 65."

Source: click here.

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